Human Insulin Resistance

Introduction

Human insulin resistance is an extremely common process, often connected with the rise in diabetes mellitus type II. The factors, which lead to the process of insulin resistance and its resulting complications, have been investigated by the majority of researchers for many years. The prerequisites for this development are studied by us, too; we provide a general view of insulin resistance and how to deal with it. Insulin resistance is when your body has become resistant to the effects of insulin, a hormone produced by the pancreas that helps control blood sugar levels. Insulin moves glucose out of your bloodstream and into your cells, which can be used for energy. If you are insulin resistant, your body’s cells don’t normally respond to the insulin you make (Beaupere et al., 2021). Insulin resistance seems to be one of the most important processes of obesity, hyperglycemia, and Type 2 diabetes.

Methods

We’re trying to find ways to help people fight type 2 diabetes. Type 2 diabetes is a problem that has no cure. People are getting it, and people have it. Doctors have to give them insulin shots, and doctors use tests to decide which people need the shots. Insulin helps them get blood sugar out of their blood, so they no longer have high blood sugar.

Results

Normally, when you eat food, your body breaks it down into glucose, used as fuel for your cells. However, insulin has to be present in the bloodstream (Hoca et al., 2021). If you’re insulin resistant, that means that your cells aren’t taking in glucose very well—and because of this, the body thinks it’s not getting enough energy from food and starts breaking down muscle and fat to use that for fuel. This is important because if your body doesn’t have enough fuel from food, it can’t function properly. In addition to causing problems with how well you digest food (and therefore affecting how much energy you have), being insulin resistant also means that you’re more likely to develop diabetes. So what can you do about this? You may be able to reverse some of the damage done by insulin resistance with lifestyle changes like eating healthier and exercising regularly (which helps decrease blood sugar levels). Still, most people need medication to manage their condition fully.

Discussion

Insulin resistance is a condition in which the body’s cells fail to respond to signals from insulin, resulting in high blood sugar levels. Insulin is a hormone that helps your cells use the sugar (glucose) they take in (Coccurello et al., 2020). When you eat or drink, your body turns the sugars and carbohydrates you consume into glucose, which it uses as fuel. Insulin tells your cells to absorb this blood glucose and use it as energy. But sometimes, insulin doesn’t work properly. Your cells don’t respond to it, so they can’t absorb the glucose in your bloodstream. As a result, more and more of it builds up in your blood, causing high blood sugar. Insulin resistance is a common reason for diabetes—a disease characterized by high glucose levels in the blood due to an inability of insulin to function correctly. However, not everyone who is insulin resistant will develop diabetes.

Having insulin resistance puts you at risk of developing type 2 diabetes if you do not change your lifestyle and overall health habits. Long-term complications of diabetes include cardiovascular disease (heart attack or stroke), nerve damage called neuropathy, kidney disease, and eye damage that can lead to blindness.

Conclusion

Insulin resistance, a type of metabolic syndrome, is a condition that occurs when your body doesn’t respond to insulin properly. Insulin is the hormone responsible for helping glucose enter the cells in your body. When your body doesn’t respond to it appropriately, you could be on your way to developing diabetes or prediabetes. But because insulin resistance can be managed with dietary and lifestyle changes, you don’t have to worry about automatically being diagnosed with diabetes if you are experiencing insulin resistance. There are several things you can do to improve insulin resistance, including eating a balanced diet, getting enough sleep, and keeping tabs on your blood sugar levels.

References

Beaupere, C., Liboz, A., Fève, B., Blondeau, B., & Guillemain, G. (2021). Molecular mechanisms of glucocorticoid-induced insulin resistance. International Journal of Molecular Sciences, 22(2), 623.

Coccurello, R., & Volonté, C. (2020). P2X7 Receptor in the management of energy homeostasis: implications for obesity, dyslipidemia, and insulin resistance. Frontiers in Endocrinology, 11, 199.

Hoca, M., Becer, E., & Vatansever, H. S. (2021). The role of resveratrol in diabetes and obesity-associated with insulin resistance. Archives of Physiology and Biochemistry, 1-7.