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Asthma and How To Treat It

Introduction

In the modern world, a sizable amount of death and morbidity is caused by chronic illnesses. Chronic asthma is now recognized as a significant worldwide health problem—there are too many healthcare stakeholders. However, asthma management and awareness are still a mirage. This is due to the complexity and unpredictability of the pharmacology and management of asthma regarding any particular case (Gilbert, 2021). This essay examines the state of our understanding regarding asthma and how to treat it.

All aspects of asthma care should include education about self-management of the disease. Patients should be reminded how to use and maintain nebulizers to solidify the information. At the time of diagnosis and during the follow-up care, it should be administered by a practicing nurse or registered nurse. Additionally, all care team members should participate in education about asthma management and treatment.

Asthma is a chronic allergic illness of the respiratory tract. It can induce coughing, respiratory problems, sneezing, and chest pains. The symptoms are connected with extensive yet varying and frequently reversible airway restriction. Asthma can be minor or severe, limiting people’s ability to live everyday life and even producing life-threatening attacks. Respiratory virus infections and environmental allergies can trigger asthma episodes. When a person is allergic to allergens such as dust or pollen, the allergen creates allergen-specific antibodies that bind to the surface of the mast cell. It subsequently causes the release of inflammatory mediators such as histamine, leukotrienes, and prostaglandins, which trigger asthma attacks.

The smooth muscles of the bronchi can enlarge due to chronic inflammation. Like people with chronic obstructive pulmonary disease, it might develop into an airway obstruction that persists over time. A body’s respiratory systems, including the lungs, deteriorate due to asthma episodes. It is essential for asthma patients to receive the proper care, take their meds as prescribed, and have regular checkups to ensure their asthma is under control. Airway oversensitivity and other potentially lethal signs can result from unmanaged asthma attacks.

Causes of Asthma

Several complicated and complex systems explain the pathophysiology of asthma. Since a very long time ago, it has been accepted medical wisdom that persons with asthma have subepithelial connective tissue in their airways that is different from that of healthy individuals. More blood vessels are seen in the tissue than in the identical places in healthy people. Even while the critical part played by bronchial arteries in the pathophysiology of asthma is now well understood, the actual mechanism is still largely unknown. The difficulty of quantifying airway blood flow is the cause of this.

Even though studying asthma presents scientific hurdles, several facts have been effectively explained. Given that a higher vascular volume is linked to airway narrowing, the bronchial circulation probably controls how wide the airways are. One possibility is that the clearance of inflammatory mediators from the airway requires increased blood flow across the airways. It needs to be clarified precisely how an asthmatic body increases the number of blood vessels.

Difficulty breathing, tightness of the chest, a whistling sound made when inhaling, and wheezing are all asthma symptoms, known as airway-hypersensitive and constricting conditions. These symptoms typically worsen at night or early morning hours and frequently wake a patient. Though it impacts individuals of all ages, asthma is commonly discovered in children. Even when one is feeling well, the recognized sickness can strike at any time and has no known treatment. A patient with chronic asthma frequently may not exhibit any signs or symptoms

despite the possibility of inflammation.

Air flow into the lungs is reduced during an acute asthma attack because the airway muscles constrict and swell, narrowing the airway. The production of thicker mucus, which further tightens a patient’s airway and leads to mucus plugs, occurs when the cells lining the airway begin to shrink. Dyspnea, chest tightness, and a decline in lung function are common in patients with trouble breathing. The management and treatment of asthma will be the main topics of this essay. This essay will also discuss the step-by-step management strategy that can aid medical professionals in managing and controlling asthma.

Quick relief and Long-Term Controlling Treatment

Albeit incurable, asthma can be managed. Asthma uniquely strikes each patient. To tailor an asthma treatment plan to a particular patient, healthcare professionals must do so. Asthma drugs can be divided into two categories: long-term controllers and fast-relievers.

Long-Term Regulation

Long-term control drugs must be taken daily to maintain control over a long period. The best medications for managing chronic symptoms and preventing asthma episodes are those that treat these conditions. Inhaled corticosteroids assist in preventing and reducing airway edema, whereas inhaled Long-Acting Beta Agonists (LABAs) help to open the airway by relaxing the smooth muscles (Beeh et al., 2017). Oral corticosteroids are recommended as therapy when a patient’s asthma episodes are unresponsive to other asthma medications. Corticosteroids and beta-agonists may occasionally be included in a single medicine. Sometimes medications that contain both beta-agonists and corticosteroids are combined. To predict a patient’s response to allergy stimuli, omalizumab (anti-IgE) is administered every two to four weeks. Leukotriene modifiers aid in improving and reducing airway edema while also relaxing the smooth muscles. When a patient is exposed to an asthma trigger, inhaling the non-steroid medication cromolyn sodium stops the airways from swelling. Theophylline medication aids in relaxing the smooth muscles, which opens the airway.

These treatments have negative impacts, and a healthcare professional’s duty is to inform a patient of these problems. Some of the main side symptoms that may occur are hoarseness of voice, coughing, and oral thrush (candidiasis). The mentioned long-term control drugs may inhibit the adrenal glands or thin the skin when taken regularly in large amounts.

Rapid-Relief Therapy

These drugs are used to treat asthma symptoms that come on suddenly. They quickly release the tight muscles encircling a patient’s airways by widening them so air can pass through. Once asthma symptoms appear, patients are advised to use their quick-relief prescriptions. Patients should speak with their healthcare provider if they utilize them more than two days per week since they may need to adjust their treatment plan. Short-Acting Beta Agonists (SABAs), inhaled to ease asthma symptoms quickly, are among these medicines (Beeh et al., 2017). They lessen edema obstructing airflow and loosen the smooth muscles surrounding the airways.

These medications are the first option for symptom alleviation that happens quickly. Inhaled anticholinergic medications open the airways by relaxing the smooth muscles and lessen mucus formation. However, they work more slowly than SABA. An anticholinergic and a short-acting beta agonist are both present in the mixture. Even while these drugs treat the symptoms, it is essential to ensure the patient understands that they may also cause adverse effects like anxiety, agitation, trembling, headaches, and rapid or irregular heartbeats.

Step-by-Step Approach to the Treatment and Management of Asthma

Asthma therapy is presently advised to be implemented in stages. Reducing the symptoms of airway blockage and inflammation is the treatment’s goal, which depends on the disease’s severity. Preventing exacerbation and preserving normal lung function are other vital goals. Glucocorticoids and 2Adrenoceptor Agonists are currently the best medications for treating asthma.

Patients who suffer from minor, severe asthma are administered daily doses of 200–500 mg of inhaled corticosteroids, hormones, or, as a substitute, consistent theophylline. Inhaled 2-adrenoceptor agonists should be administered to patients to treat an acute asthma flare, but no more than three or four times per day is recommended. Elevated doses of 800-2,000 mg of inhaled corticosteroids and long-acting two adrenoceptor agonists are required to treat moderate persistent asthma. Sustained-release theophylline or long-acting oral two adrenoceptor agonists should be administered to patients who experience symptoms at night.

Short-acting bronchodilators may be beneficial for treating acute symptoms, but they should not be used more than three to four times daily. Increasing the dosage of inhaled steroids may not be as beneficial for certain persons as incorporating a long-acting two agonist or low-dose theophylline. Finally, long-acting 2adrenoceptor blockers are needed for severe chronic asthma and inhaled corticosteroids at 800–2,000 g. A slow, stepwise dose reduction is advised if a patient can maintain asthma control for over three months.

According to researchers, there is now no practical alternative to the aforementioned medications or anything that might have better results. Inhaled steroid medication combinations are encouraged by the National Health Institutes, preferably in conjunction with long-acting two adrenoceptor agonists. They were picked because of their increased effectiveness and possible steroid-sparing effects. Due to varying healthcare availability and patient convenience, treatment options vary by nation. The likelihood of side effects should be considered when choosing the appropriate drug (Dalton & Byrne, 2017). Last, the treatment choice is influenced by the therapy price and applicable reimbursement regulations.

Diagnose, Diagnose, and Educate the Patient

The National Institutes of Health (NIH asthma )’s care reference guide contains recommendations for evaluation, diagnosis, and patient education for medical personnel caring for individuals with asthma. The first visit should include a diagnosis, an evaluation of the seriousness of asthma, the administration of medicine, the creation of an action plan, and the scheduling of follow-up consultations, according to the healthcare institutions. In order to diagnose asthma, a patient’s anamnesis and examination must reveal signs of recurring airway blockage (Farag et al., 2018).

A history of coughing, wheezing, breathing problems, and a sensation of tightness in the chest area, mainly if they are repeated, are some of the factors that need to be considered. If the symptoms mentioned above appear or worsen at night or when a patient is physically active, they are likely signs of asthma in that patient. The NIH advises spirometry to identify airway blockage in patients older than five years. The fact that additional causes of lung blockages should be considered is essential to emphasize for validity.

According to the National Institutes of Health (NIH), asthma is a long-term but manageable condition. The National Institutes of Health (NIH) argues that controlling asthma has two essential functions. A solid asthma management plan should, first and foremost, aim to lessen impairment by easing the frequency and severity of symptoms. Also, asthma management should assist patients in lessening or eliminating any functional restrictions they may be dealing with (Liao et al., 2018).

Reducing risk is the second goal of asthma control under medical supervision. Avoiding severe asthma attacks and the gradual deterioration of lung function brought on by the biological changes mentioned in the preceding section is crucial. Last but not least, managing the adverse effects of medicine, which play a big part in asthma control.

Patients with asthma want to avoid signs, lessen acute-event mortality, and lead healthy lifestyles without flare-ups or epidemics. The stepwise method of treating and managing asthma is a six-step process in which the number, dosage, and frequency of drugs are raised as needed while symptoms continue and then lessened when objectives are met and sustained.

Controlling asthma should involve both medical experts and asthma patients working together. A healthcare professional can only do so much to monitor the disease’s development and prescribe medicine. Patients with asthma must be knowledgeable and responsible enough to manage their health because they are frequently left to fend for themselves. The National Health Institutes advise doctors to promote and support self-monitoring and medication adherence at each appointment. Patients need to be taught how to evaluate the intensity of their symptoms and be alert to the warning signals of asthma worsening concerning the former.

In relation to the latter, patients must comprehend how to utilize an inhaler and other tools and distinguish between long-term and short-term drugs. Medication used for long-term control is preventative; corticosteroids, for example, lessen airway irritation. Some patients prefer short-term drugs like short-acting beta2-agonists or SABAs that relax the muscles of the airways since they have a cumulative impact that may not be visible all at once. Sadly, people who misuse these drugs risk developing resistance and finding that their go-to method of treating their asthma no longer works. A health practitioner must inform patients of these adverse effects and guide them on proper pharmaceutical use.

Creating an action plan that can be maintained for long periods is another crucial component of patient education. There is no one-size-fits-all approach to managing asthma; each patient’s needs and preferences must be carefully considered when developing an asthma control strategy. First and foremost, it is essential to pinpoint the environmental factors—specific meals, scents, or living environments—that cause asthma attacks (Liao et al., 2018). A patient can continue with the technique and modify daily habits after becoming aware of personal triggers. A patient may be taking other drugs, so it is essential to find out what they are and keep an eye on how they interact with one another.

Some drugs might not be suitable for people with asthma and could worsen their illnesses. A healthcare provider should develop a strategy based on patient-friendly little steps that will help them maintain their health and avoid negative consequences after considering all of these factors. A healthcare professional should always be understanding and upbeat to increase patients’ belief in their capacity to manage their illness.

The National Institutes of Health also emphasizes the value of family support and participation. Asthma can be complicated to manage because it is a severe and sometimes fatal scenario (Margolis et al., 2019). For this reason, it is recommended that medical personnel consult with and inform a patient’s family. It should be mentioned that the recovery period involves not only family members but also other health specialists. According to the NIH, all healthcare professionals should work together to educate patients, including doctors, chemists, medics, health workers, and asthma instructors.

For prompt symptom alleviation, SABA bronchodilators are necessary for all asthma patients, irrespective of their severity. The intensity of the illness determines medication, and when quick-acting medication is utilized for symptom control on more than two days per week, scaling up is required (Domingo et al., 2019). Patients get reevaluations one to 3 months into their medication and every three to twelve months after that. If symptoms are effectively controlled after three months of treatment, the dosage can be reduced. Treatment reduction is carried out methodically while signs and symptoms are closely watched. Before advancing to a more rigorous drug regimen, evaluating medication compliance and environmental sensitivities is essential.

Health Care Providers and Patients Benefit from Stepwise Management

Patients and healthcare professionals can use the stepwise method to improve asthma therapy. By reducing the overuse of needless pharmaceuticals and determining the efficacy of medications, this technique can help (May et al., 2017). Reevaluating patients every three to twelve months allows medical professionals to ascertain whether a patient is following the prescribed regimen, whether triggers are causing symptoms to worsen, or whether the patient’s existing meds are not managing the signs. It improves both patients and healthcare professionals in detecting the circumstances of asthma and comprehending how to control and treat the symptoms since it encourages an understanding of the disease. To put it another way, stepwise management enhances the standard of care by reducing the risk of patient problems and overdose while also making it clear to medical professionals how to handle a specific patient.

It improves both patients and healthcare professionals in detecting the circumstances of asthma and comprehending how to control and treat the symptoms since it encourages an understanding of the disease. To put it another way, stepwise management enhances the standard of care by reducing the risk of patient problems and overdose while also making it clear to medical professionals how to handle a specific patient.

Interventions

Establishing and implementing a so-called medical home for the asthma program is one tactic that could result in implementing change concerning the treatment of asthma (Agusti et al., 2021). Children from low-income families would be the program’s focus, which aimed to address the lack of continuity in primary care. “Medical homes” may operate out of office at a hospital or other healthcare facility. Giving patients thorough information would be the “medical asthma home main “‘s duty. Even though full patient consultations are one of the components of adherence promotion, healthcare professionals frequently need more time to do so. Patients may be referred to a “medical home” to receive the necessary care.

The development, publication, and dissemination of asthma control materials could be another goal of the proposed intervention. Nowadays, many patients look for information online, but with the proper instruction and training, they might be able to tell which trustworthy sources. “Medical homes” may take care of this by reviewing the sources, compiling them, and making recommendations to the patients. The primary assessment metric for this intervention will be patient satisfaction. Regular surveys could be used to gauge how happy patients are with their time spent at the facility.

Enhancing ongoing education among clinicians, who frequently lack the skills and resources to support asthma patients, is another potential solution. A brief study program could provide continuous learning, educating medical practitioners on neglected facets of managing asthma and enhancing their communication abilities (Miles et al., 2017). The study plan could be developed under the guidance of the self-regulation theory, which was taken from the psychology sector. According to the self-regulation idea, people can manage their urges and hold themselves responsible for their actions. Being mindful and conscious of one’s activities is what is meant by self-regulation in this situation.

Guidelines for ideal clinical practice conformance with the guidelines developed by the National Institutes of Health (NIH) and improving patient training and communication should be the seminar’s two primary focuses (Knapp et al., 2022). A series of brief lectures by invited asthma specialists opened the session. Videos that illustrate, among other things, successful treatment connections and patient education strategies are presented in conjunction with the lectures. Summarizing the main theoretical points is insufficient; thus, health practitioners can resolve real-world situations that represent typical asthma control and management situations.

Last but not least, invited lecturers and couches could analyze the information and sources available regarding managing asthma and highlight those suitable for advising patients. Both immediately following the seminar and throughout time could be used to gauge how effective the intervention was. The healthcare facility could set up a quiz right after the session to gauge how well the attendees comprehended the subject matter. The long-term impacts might be harder to identify; they might show up in the frequency of readmissions, adherence to therapy, and patient satisfaction.

The third approach is the recent advancement of technology in medicine. Although the guidelines for treating asthma are very well, it can be challenging to get patients to adhere to them in practice (Bosquet et al., 2020). The patients’ over-dependence on “rescue medication” is one of the biggest problems with asthma control. Short-term asthma treatments should only be taken in an urgent situation, as has already been indicated, and patients should not take them more frequently than three to four times per week. Merchant et al. (2018) effectively address the stated issue and might be applied in our healthcare organization.

Electronic medication monitors (EMMs) were a component of the intervention that recorded inhaler medications use. A digital model with extensive information for both doctors and patients was used as an additional tool by Merchant et al. (2018). The percentage of people who utilize “emergency” medications is the ideal performance measure for this intervention. A decline in the use of short-term asthma treatment is the desired result.

Conclusion

To sum up, asthma is a chronic ailment that frequently goes untreated due to variables like disease progression, symptom management by medical professionals, patient views of the condition, self-management techniques, or a combination of these. Overall, asthma treatment aims to manage and control symptoms so a patient can have a comfortable life. These objectives can be significantly helped by medication and the stepwise method. Quick-relief medication should be used to respond to asthma symptoms quickly and get rid of them, but long-term management is necessary to maintain control. Although there is no cure for asthma, symptoms can be managed in addition to treating the disease’s symptoms by identifying early triggers.

References

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Beeh, K. M., Burgel, P. R., Franssen, F. M., Lopez-Campos, J. L., Loukides, S., Hurst, J. R., … & Wedzicha, J. A. (2017). How do dual long-acting bronchodilators prevent exacerbations of chronic obstructive pulmonary disease? American journal of respiratory and critical care medicine196(2), 139-149.

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Dalton, K., & Byrne, S. (2017). Role of the pharmacist in reducing healthcare costs: current insights. Integrated pharmacy research & practicepp. 6, 37.

Domingo, C., Rello, J., & Sogo, A. (2019). As-needed ICS-LABA in mild asthma: what does the evidence say? Drugs79(16), 1729-1737.

Farag, H., Abd El-Wahab, E. W., El-Nimr, N. A., & Saad El-Din, H. A. (2018). Asthma action plan for proactive bronchial asthma self-management in adults: a randomized controlled trial. International Health10(6), 502-516.

Glinert, L. H. (2021). Communicative and discursive perspectives on the medication experience. Pharmacy9(1), 42.

Knapp, A. A., Carroll, A. J., Mohanty, N., Fu, E., Powell, B. J., Hamilton, A., … & Smith, J. D. (2022). A stakeholder-driven method for selecting implementation strategies: a case example of pediatric hypertension clinical practice guideline implementation. Implementation science communications3(1), 1–14.

Liao, S. Y., Zeki, A. A., & Jarjour, N. (2020). Difficult Asthma: Unmet Needs and Future Directions. In Difficult To Treat Asthma (pp. 313-324). Humana, Cham.

Margolis, R. H., Bellin, M. H., Bookman, J. R. M., Collins, K. S., Bollinger, M. E., Lewis-Land, C., & Butz, A. M. (2019). Fostering effective asthma self-management transfer in high-risk children: gaps and opportunities for family engagement. Journal of Pediatric Health Care33(6), 684–693.

May, J. R., & Dolen, W. K. (2017). Management of allergic rhinitis: a review for the community pharmacist. Clinical therapeutics39(12), 2410–2419.

Miles, C., Arden-Close, E., Thomas, M., Bruton, A., Yardley, L., Hankins, M., & Kirby, S. E. (2017). Barriers and facilitators of effective self-management in asthma: a systematic review and thematic synthesis of patient and healthcare professional views. NPJ primary care respiratory medicine27(1), 1–21.

 

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