Voice production among humans depends on the softness of the mouth lining and the level of protection of the vocals chords against chemicals, bacterial, and physical attacks; the clarity and voice eloquence of human voice depends on the level of protection the vocal cords have due to the presence of a protective lining on the outermost part of the vocal cords.
Found in the larynx. The stratified squamous and epithelium tissues are responsible for the protection against any chemicals and biological insults to which the chords might be subjected. The stratified squamous are closely packed cells, joined together by protein complexes referred to as a cell’s junctions (Chalmers et al., 2022)). The junction act as structural support to the epithelium cells since they provide structural support to the cells, and re-closed packaging of the cells provide physical barriers to the s delicate vocal cords. The s stratified squamous epithelium is multilayered and hence irritant-proof. The quality of speech and voice production depends on the closeness of the epithelial tissues.
Abnormalities in the stratified squamous tissues include nodules, polyps, and granulomas. These disorders compromise the quality of speeches and sound production since they necessitate attacks on the vocal cords. Disorder on the epithelium results in a lack of vocal defense because the nodules restrict the systematic vibrations of the chords, inhibiting the quality of the voice produced. Structural abnormalities in the stratified squamous include compromised cell junctions, a lack of protein substrates in the epithelial cells, and structural disorders such as the lack of a multilayer system in the epithelial cells. The lack of close cell junctions between the stratified Squantum’s epithelium increases granulomas and nodules’ attack on the chords. Since the cells are closely held together by the protein substrate, which is critical to the structural and mechanical supports, the lack of substrates in the cell boundaries compromises the structural integrity of the epithelium, leading to rosiness, a common vocal cord disorder.
Vocal cord paralysis is a condition that prevents one from controlling the muscles that are key to voice production. The overall effect of paralysis is one’s inability to speak or even breathe due to the lack of proper coordination of the muscles. This deadly condition occurs from polyps within the stratified squamous. The presence of nodules, which are abnormal swellings on the vocal cords, results in bacterial attacks of the cords in the larynx, which leads to insensitivity to the movement of the muscles. The primary causes of vocal chord paralysis also include compromised integrity in the structures of the stratified squamous epithelium. Usually, the cells are multilayered, and the close knitting in the structure of the cells results in a considerable looseness in the vocal cords s, supports, and muscles, which in turn leads to a lack of coordination in the movements of the chords.
The junction between the stratified squamous epithelium cells is regularly closed. Junctional disorders are deadly abnormalities that epithelial cells are subjected to. The abnormalities related to junctions are desmosomes, gaps, and closed junctions (Whittle et al ., 2023). Desmosome junctions occur as a result of adhesive interactions between adjacent epithelial cells. The adhesives force at the boundaries results in repellence which compromises the continuous linings of eths stratifies squamous. These gaps expose the epithelial cells to biological, physical, and chemical attacks. Which desmosomes have, in turn, compromised voice production, The bacterial attack that affects the vocal cords due to desmosomes is laryngitis. This condition is characterized by straining when talking, yelling, or singing. Laryngitis is a severe vocal cord issue that, without prior checking, could result in permanent voice loss. Gap junctions, conversely, are caused by the depletion of the epithelial layers, which result in the attacks of yeasts and other bacterial infections on the vocal cords. In most cases, a sore throat and inflammation of the voice box are caused by gaps in the stratified squamous. Desmosomes result in mechanical stress in eth cells and the vocal muscles, leading to a high vulnerability to bacterial infections.
Vocal cord dysfunction is a chemically-induced irritation due to disorders in the epithelial cells. The deadly inflammatory condition, which results from laryngeal dysfunctions, causes the vocal cords to experience stiffness, producing wheezing sounds. The uneven distributions of keratin cells bring about nodules and swellings in the stratified squamous epitheliums (Szabó et al ., 2019). Since the stratified squamous is composed of keratins, a substance that makes them water-proof, they protect the vocal cords from getting soaked and prevent bacteria from infecting them. Swelling of the stratified squamous therefore makes the vocal cords vulnerable to bacterial and chemical attacks, affecting voice production.
In conclusion, the stratified squamous cell is protective in speech production. Their structural and chemical composition make them keys to the immune system. Even sexually transmitted diseases affecting the vocal cords are prevented by the epithelial cells in the larynx. Therefore, speech production and restoration of the stratified squamous’s qualities are essential in voice production and chewing health.
References
Chalmers, F. E., Dusold, J. E., Shaik, J. A., Walsh, H. A., & Glick, A. B. (2022). Targeted deletion of TGFβ1 in basal keratinocytes causes profound defects in stratified squamous epithelia and aberrant melanocyte migration. Developmental biology, 485, 9-23. https://doi.org/10.1016/j.ydbio.2022.02.009
Szabó, D., Kovács, D., Endrész, V., Igaz, N., Jenovai, K., Spengler, G., … & Rovó, L. (2019). Antifibrotic effect of mitomycin‐C on human vocal cord fibroblasts. The Laryngoscope, 129(7), E255-E262. https://doi.org/10.1002/lary.27657
Whittle, C., Silva‐Hirschberg, C., Loyola, K., Fajre, X., & Andrews, A. (2023). The ultrasonographic spectrum of cutaneous cysts with stratified squamous epithelium in pediatric dermatology: a pictorial essay. Journal of Ultrasound in Medicine, 42(4), 923-930. https://doi.org/10.1002/jum.16051
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